Searchable abstracts of presentations at key conferences in endocrinology

ea0037gp.24.01 | Thyroid–genetics | ECE2015

Prox1 transcription factor is differentially expressed in thyroid cancer and contributes to the regulation of invasion and migration of thyroid cancer cells

Rudzinska Magdalena , Gawel Damian , Karpinska Kamila , Kiedrowski Miroslaw , Stepien Tomasz , Marchlewska Magdalena , Krasuska Wanda , Ledwon Joanna , Macios Maria , Lange Dariusz , Czarnocka Barbara

Introduction: The differentiated thyroid cancer (DTC) is the most frequent endocrine malignancy with the incidence increasing worldwide. Although, DTCs are considered to be mostly indolent lesions, the proportion of patients develop metastases. Therefore, identification of molecular factors that are involved in thyroid tumour progression might help to better understand the mechanism of thyroid cancer metastasis. In the present study we examine the role of the transcription fac...